Enteric Dissolution Failures
- Rapid dissolution in pH < 2
- Poor enteric protection
Guaranteed Resolution: Whether failing at Acid Stage (0.1N HCl) or Buffer Stage (pH 6.8).
From resolving complex tablet coating defects to complete process optimization, ANSHCOAT's technical experts provide comprehensive troubleshooting backed by decades of pharmaceutical manufacturing experience.
While most manufacturers use the same base enteric polymers, the difference lies in the formulation. ANSHCOAT’s proprietary enteric systems are extensively proven and rigorously tested across challenging APIs, including the entire prazole group (Omeprazole, Pantoprazole, Esomeprazole), Aspirin, Bisacodyl, and many more. Our optimized formulations guarantee a dense, impermeable film that consistently passes both stringent acidic stage (0.1N HCl) requirements and sharp buffer stage (pH 6.8) release profiles.
Yes. We tackle highly hygroscopic APIs using two advanced, proven approaches. Depending on the exact sensitivity of your core, we utilize either our robust Ethyl Cellulose and HPMC-based coating systems, or our specialized PVA + Lecithin-based moisture barriers. Both formulations are proven to drastically lower Moisture Vapor Transmission Rates (MVTR) and provide guaranteed results against blistering and gas formation.
Cosmetic defects require expert diagnosis, not just a generic product. When you face issues like rough films or undispersed color dots, we first discuss the issue in depth to understand the exact problem at the machine or formulation level. From there, our highly experienced R&D team will either suggest immediate process parameter adjustments or custom-design the best-suited coating material to resolve the defect entirely.